Marcel Salathé

1 0 1 0 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 1 1 0 1 1 0 0 1 0 1 0 1 0 1 0 0 0 1 0 0 1 0 0 1 0 1 0 1 1 0 1 1 0 0 1 0 1 0 1 1 0 0 0 1 0 0 1 1 1 0 0 0 1 0 0 1 0 0 1 0 1 0 0 1 0 0 1 1 1 0 1 0 0 0 0 1 0 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 1 1 1 0 0 1 0 1 1 0 1 1 1 0 1 0 0 1 1 1 0 1 1 0 0 1 0 1 0 1 0 0 0 1 0 0 0 0 1 0 0 1 1 1 0 1 0 0 1 1 1 0 1 1 0 0 1 0 1 0 1 0 1 0 0 0 1 0 0 1 0 0 1 0 1 0 1 0 0 1 1 1 0 1 1 0 0 1 0 0 0 1 0 0 1 1 1 1 0 0 1 1 1 0 1 1 0 1 0 0 1 0 1 0 1 1 0 0 1 s a l a t h e . c o m 0 0 1 0 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 1 1 0 1 1 0 0 1 0 1 0 1 0 1 1 0 1 0 1 0 0 0 1 0 0 1 0 0 1 0 0 1 0 0 1 1 1 0 1 1 0 0 1 0 1 0 1 0 1 0 0 0 1 0 0 1 0 0 1 1 1 1 0 1 1 0 1 0 0 1 0 0 1 1 1 1 0 1 0 0 1 0 0 1 1 0 0 1 0 0 1 1 0 1 1 0 0 1 0 1 1 1 1 0 1 0 0 0 0 1 1 1 0 1 1 0 0 1 0 0 0 0 0 0 1 0 0 1 1 1 0 0 0 1 0 0 1 0 0 1 0 1 0 0 1 0 0 1 1 1 0 1 1 0 1 0 1 0 0 0 1 0 0 0 0 1 0 0 1 1 1 0 1 0 0 1 1 1 0 1 1 0 0 1 0 1 0 1 0 1 0 0 0 1 0 0 1 0 0 1 0 1 0 1 0 0 1 1 1 0 1 1 0 0 1 0 0 0 1 0 0 1 1 1 1 0 0 1 1 1 0 1 1 0 1 0 0 1 0 1 0 1 1 0 0 1

Science

September 25th 2008


Update November 2008: The recent MSB article "Parasites lead to Evolution of Robustness against Gene Loss in Host Signaling Networks" has has been a top ten download on the Nature MSB website (http://www.nature.com/msb/topten/index.html). Update September 2008: The recent MSB article "Parasites lead to Evolution of Robustness against Gene Loss in Host Signaling Networks" has been featured in the 24. Sept. issue of Nature: "The paper is an exciting invitation to take a computational approach to evolutionary questions, by including more detailed mathematical representations." More... Update August 2008: The recent TREE article "The state of affairs in the kingdom of the Red Queen" has been selected by F1000 as a recommendation in the Ecology section: "This paper excellently summarizes the state of the art with respect to the Red Queen hypothesis (RQH), pointing out issues of controversy, new theoretical findings, and issues for future research." More...

Publications


On the Causes of Selection for Recombination underlying the Red Queen Hypothesis Marcel Salathé, Roger D. Kouyos & Sebastian Bonhoeffer American Naturalist, in review TBA

The Role of Epistasis on the Evolution of Recombination in Host-Parasite Coevolution Roger D. Kouyos, Marcel Salathé, Sarah P. Otto & Sebastian Bonhoeffer Theoretical Population Biology, accepted, in print TBA

The Effect of Opinion Clustering on Disease Outbreaks Marcel Salathé & Sebastian Bonhoeffer Journal of The Royal Society Interface, First Cite » Abstract

The State of Affairs in the Kingdom of the Red Queen Marcel Salathé, Roger D. Kouyos & Sebastian Bonhoeffer Trends in Ecology & Evolution, 23:8, 439-445 (2008) » Abstract

Parasites lead to Evolution of Robustness against Gene Loss in Host Signaling Networks Marcel Salathé & Orkun S. Soyer Molecular Systems Biology, 4:202 (2008) » Abstract

Rapid Parsite Adaptation drives Selection for High Recombination Rates Marcel Salathé, Roger D. Kouyos, Roland R. Regoes & Sebastian Bonhoeffer Evolution, 62-2, 295-300 (2008) » Abstract & PDF

The Red Queen and the Persistence of Linkage Disequilibrium Oscillations in Finite and Infinite Populations Roger D. Kouyos, Marcel Salathé & Sebastian Bonhoeffer BMC Evolutionary Biology, 7:211 (2007) » Abstract & PDF

Sexual Selection and its Effect on the Fixation of an Asexual Clone Marcel Salathé Biology Letters, 2, 536-538 (2006) » Abstract & PDF

Mutation Accumulation in Space and the Maintenance of Sexual Reproduction Marcel Salathé, Rahel Salathé, Paul Schmid-Hempel and Sebastian Bonhoeffer Ecology Letters, 9 (8), 941-946 (2006) » Abstract & PDF

High Epitope Expression Levels Increase Competition Between T Cells Almut Scherer, Marcel Salathé and Sebastian Bonhoeffer PLoS Computational Biology, 2(8): e109 (2006) » Abstract & PDF

The Effect of Multifunctionality on the Rate of Evolution in Yeast Marcel Salathé, Martin Ackermann and Sebastian Bonhoeffer Molecular Biology and Evolution, 23 (4), 721-722 (2006) » Abstract & PDF

Signal Transduction Networks: Topology, Response & Biochemical Processes Orkuns S. Soyer, Marcel Salathé and Sebastian Bonhoeffer Journal of Theoretical Biology, 238 (2) (2006) » Abstract & PDF

The Evolution of Network Topology by Selective Removal Marcel Salathé, Robert M. May and Sebastian Bonhoeffer Journal of The Royal Society Interface, 2(5): 533-536 (2005) » Abstract & PDF

Neutral Drift & Polymorphism in Gene-for-Gene Systems Marcel Salathé, Almut Scherer and Sebastian Bonhoeffer Ecology Letters, 8: 925-932 (2005) » Abstract & PDF

Awards

Society in Science: The Branco Weiss Fellowship (awarded 2008) Postdoctoral Fellowship Swiss National Science Foundation (awarded 2007) ETH Medal for outstanding PhD thesis (awarded 2007)

Scientific path

I studied Biology at the University of Basel with Dieter Ebert, Tad Kawecki, Michael Doebeli and Steve Stearns. I then did a PhD with Sebastian Bonhoeffer at the ETH in Zurich. Since 2008, I am a PostDoc in Marc Feldman's group at Stanford. I'm currently working on the consequences of host-parasite coevolution. From October 2008 on I will be a Branco Weiss fellow working on questions about the non-genetic (e.g. cultural & epigenetic) effects on disease dynamics. Back home